Clinical Observation of Short-Term Effect of Methylpre Dnisolone Pulse Therapy on in an Oxygen-rich Environments Acute Spinal Cord Injury

Xianghui Dong, Donglei Yue, Pengzhen Lei, Binya Shi, Zhengming Sun, Yanhai Chang, Ming Ling

Ekoloji, 2019, Issue 108, Pages: 355-360


Download Full Text (PDF)


To observe and analyze the short-term efficacy of methylprednisolone pulse therapy in the treatment of acute spinal cord injury, and provide valuable guidance for clinical treatment. The patients were divided into study group (100 cases) for methylprednisolone pulse therapy and reference group (100 cases) for dexamethasone therapy. The treatment outcomes of the two groups were statistically compared. Results: Comparison of the overall treatment effectiveness of the two groups shows significant advantage of the study group over the reference group, p <0.05; Conclusion: Methylprednisolone pulse therapy has a good short-term effect on acute spinal cord injury, which can promote patient recovery with great application value.


  • Eiber M, Fingerle AA, Brüge lM (2016) Detection and classification of focal liver lesions in patients with colorectal cancer: Retrospective comparison of diffusion weighted MR imaging and multi-slice CT. European Journal of Radiology 81 (4):683-691.
  • Jiang J H, Han P, Ye C R. (2016) Application of medium and large dose methylprednisolone in thoracolumbar fracture and acute spinal cord injury. Journal of Mudanjiang Medical University 37 (03): 80-81.
  • Koshiyama A, Ichibangase T, Imai K. (2017) Comprehensive fluorogenic derivatization liquid chromatography tandem mass spectrometry proteomic analysis of colorectal cancer cell to identify biomarker candidate. An
  • International Journal Devoted to Research in Chromatographic Methodologies and Their Applications in the Biosciences 27 (4):440-450.
  • Ma J, Wang L, Yang Y, Qiao Z, Fang D, Qiu X, Yang X, Zhu X, He J, Pan H, Ban B, Zhao Y, Sui H (2017) GNB3 and CREB1 gene polymorphisms combined with negative life events increase susceptibility to major depression in a Chinese Han population. Plos One 12 (e01709942)
  • Saylan Cevik B, Akalin F, Erolu E, Gencosmanoolu S, Ergun T (2019) Assessment of cardiac and vessel functions in childhood psoriasis. Turkish Journal of Medical Sciences 49 (2): 617-623.
  • Shah C, Zhang W, Xiao Y, Yao L, Zhao Y, Gao X, Liu L, Liu J, Li S, Tao B, Yan Z, Fu Y, Gong Q, Lui S (2017) Common pattern of gray-matter abnormalities in drug-naive and medicated first-episode schizophrenia: a multimodal meta-analysis. Psychological Medicine 47 (3): 401-413.
  • Wang C, Zhao M, Liu YR (2018) Suppression of colorectal cancer subcutaneous xenograft and experimental lung metastasis using nanoparticle mediated drug delivery to tumor neovasculature. Biomaterials 35 (4):1215-1226.
  • Zhao WT, Yuan HB, Li PP, Zhang HF, Liu MQ. (2015) Repair of acute spinal cord injury by methylprednisolone. meta-analysis on the effects and adverse reactions. Clinical Rehabilitative Tissue Engineering Research 19 (42): 6868-6874.