Combined Therapy of IL-2 and IFN-Α on Immune Function of Postoperative Patients with Liver Cancer in Ecological Environment

Jincai Shang, Zhiwu Ji, Hao Tian, Xin Lv, Ruigang Chen, Xingquan Wang, Dewang Su

Ekoloji, 2019, Issue 108, Pages: 277-281


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The effect of combined therapy of IL-2 and IFN-α on immune function of postoperative patients with liver cancer was observed and analyzed in ecological environment. The 160 patients with liver cancer who received treatment in our hospital were selected as research objects, all of whom were applied with treatment for liver cancer. All the patients in this study enjoyed the right to know and signed informed consent before study. The patients were divided into research group and control group, each containing 80. The patients in control group were treated with IFN-α after operation, while patients in research group were applied with combined therapy of IL -2 and IFN. Before the treatment, there was no significant difference in SIL-12 level between research group and control group, P > 0.05; After implementing different treatments, theSIL-12 level in research group increased significantly, which was significantly higher than that of control group, P < 0.05. In addition, the levels of CD3+, CD4+, CD8+, CD56+in research group after treatment were also significantly superior to control group, and the intergroup difference was of statistical significance, P < 0.05. The combined therapy of IL-2 and IFN-αwould effectively improve the immune function of postoperative patient with liver cancer and obtain better prognosis, which should be promoted clinics.


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